Skip to content

Dr. Chris Sutton,
Associate Professor

Information about Dr. Chris Sutton at the University of Bradford.

School of Chemistry & Biosciences
(Faculty of Life Sciences)
Email:
c.w.sutton@bradford.ac.uk
Telephone:
+44 1274 236480
Photo of Dr. Chris Sutton

Biography

Chris Sutton obtained his B.Sc. degree and Ph.D. in Biochemistry from University of Liverpool, with combined studies in the Department of Plant Molecular Biology, University of California, Berkeley. He was then a Postdoctoral Research Scientist at the London School of Hygiene and Tropical Medicine, investigating the mechanisms of pathogenicity of Vibrio cholerae.He joined the premier of UK biotechnology company, Celltech Limited, as a Senior Scientist in Protein Biochemistry purifying novel proteins of therapeutic interest, and was later promoted to Group Leader of Analytical Biochemistry. With the emergence of mass spectrometry for protein characterisation, he moved to ThermoFinnigan and developed novel applications for matrix assisted laser desorption mass spectrometry (MALDI MS) including pioneering work in proteomics. He joined Kratos Analytical as MALDI MS Product Manager and was responsible for the marketing and promotion, including co-ordinating the research activity of a worldwide group of 25 application specialists who were developing MALDI MS solutions for the future. He was subsequently promoted to Business Manager for the product lines with a staff of 50, doubling revenues during this time to 10 million USD per annum.Since August 2005, Chris has joined the Institute of Cancer Therapeutics in the University of Bradford as Senior Lecturer in Proteomics Chemistry and Mass Spectrometry. With the support of Yorkshire Cancer Research, he has develop three key areas of research (1) identification of new proteins as candidate diagnostic biomarkers, (2) identification of proteins affected by the action of anticancer drugs and (3) identification of new target proteins for anticancer drug development. He has developed collaborations with academic groups in Hull, York, Sheffield and Leeds within the UK and Toronto, Cyprus, Pakistan internationally.

Research

Proteomics and mass spectrometry. Current Projects.

  • Identification of biomarkers for the early detection of breast cancer
  • Characterisation of drug resistance mechanisms in colorectal and breast cancer
  • Proteomic stratification of head and neck cancers
  • Profiling cytochrome P450s isoforms in cancer tissues and cell lines
  • Influence of microenvironmental changes on cancer cell phenotype
  • investigation and characterisation of close proximity derived liquid biopsies/biofluids

Professional activities

Information about education, employment and areas of particular interest for Dr. Chris Sutton is as follows:

Employment

  • University of Bradford, Bradford, West Yorkshire - Senior Lecturer in Proteomics and Mass Spectrometry in the year 2005 (specified as 01/01/2005)
  • Oxford Instruments, Abingdon, Oxon - Proteomics and Mass Spectrometry Consultant in the year 2005 (specified as 01/01/2005)
  • Shimadzu Corporation, Trafford, Manchester - Mass Spectrometry Business Manager in the year 2001 (specified as 01/01/2001)
  • Shimadzu Corporation, Trafford, Manchester - Mass Spectrometry Product Manager in the year 1998 (specified as 01/01/1998)
  • Thermo Scientific, Hemel Hempstead, Herts. - Product Manager in the year 1996 (specified as 01/01/1996)
  • Thermo Scientific, Hemel Hempstead, Herts. - Senior Research Biochemist in the year 1991 (specified as 01/01/1991)
  • Celltech Limited, Slough, Berks. - Group Leader of Analytical Biochemistry in the year 1989 (specified as 01/01/1989)
  • Celltech Limited, Slough, Berks. - Senior Research Scientist in the year 1985 (specified as 01/01/1985)
  • London School of Hygiene and Tropical Medicine, London - Wellcome Foundation Postdoctoral Research Scientist in the year 1982 (specified as 01/01/1982)

Education

  • Liverpool - PhD
  • Liverpool - BSc (Hons)

Publications

There are 13 publications involving or that are attributed to Dr. Chris Sutton. They are listed as:

  • conference publication (2)
  • peer reviewed journal (11)

Conference Publication

Dr. Chris Sutton has 2 publication(s) listed under conference publication.
Title Year Publication name Journal Volume Pages Authors Editors ISSN Publisher DOI Location
2015 Microarray big data integrated analysis to identify robust diagnostic signature for triple negative breast cancer Microarray big data integrated analysis to identify robust diagnostic signature for triple negative breast cancer Zaka, Masood-Ul-Hassan; Peng, Yonghong; Sutton, Chris W.
2014 Integrated microarray analytics for the discovery of gene signatures for triple-negative breast cancer Integrated microarray analytics for the discovery of gene signatures for triple-negative breast cancer Zaka, Masood-Ul-Hassan; Peng, Yonghong; Sutton, Chris W.

Peer Reviewed Journal

Dr. Chris Sutton has 11 publication(s) listed under peer reviewed journal.
Title Year Publication name Journal Volume Pages Authors Editors ISSN Publisher DOI Location
Characterization of Changes in the Proteome in Different Regions of 3D Multicell Tumor Spheroids 2012 McMahon, Kelly M.; Volpato, Milène; Chi, H.Y.; Musiwaro, P.; Poterlowicz, Krzysztof; Peng, Yonghong; Scally, Andy J.; Patterson, Laurence H.; Phillips, Roger M.; Sutton, Chris W.
Quantitative proteomic profiling of matched normal and tumor breast tissues. 2010 Sutton, Chris W.; Rustogi, Nitin; Gurkan, C.; Scally, Andy J.; Loizidou, M.A.; Hadjisavvas, A.; Kyriacou, K.
Thin-layer chromatography/matrix-assisted laser desorption/ionisation mass spectrometry and matrix-assisted laser desorption/ionisation mass spectrometry imaging for the analysis of phospholipids in LS174T colorectal adenocarcinoma xenografts treated with the vascular disrupting agent DMXAA 2015 Rapid Communications In Mass Spectrometry 29 1288 - 1296 Batubara, A.; Carolan, V.A.; Loadman, Paul M.; Sutton, Chris W.; Shnyder, Steven D.; Clench, M.R. doi.org/10.1002/rcm.7223
Rational development of novel activity probes for the analysis of human cytochromes P450 2016 ChemMedChem Sellars, J.D.; Skipsey, M.; Sadr-ul-Shaheed; Gravell, Sebastian; Abumansour, Hamza M.A.; Kashtl, Ghasaq; Irfan, Jawaria; Khot, Mohamed; Pors, Klaus; Patterson, Laurence H.; Sutton, Chris W.
Identification of Stage-Specific Breast Markers using Quantitative Proteomics 2013 Shaheed, Sadr-ul; Rustogi, Nitin; Scally, Andy J.; Wilson, J.; Thygesen, H.; Loizidou, M.A.; Hadjisavvas, A.; Hanby, A.; Speirs, V.; Loadman, Paul M.; Linforth, R.; Kyriacou, K.; Sutton, Chris W.
Patterns of cancer cell sphere formation in primary cultures of human oral tongue squamous cell carcinoma and neck nodes 2014 Saleem, Saira; Jamshed, A.; Faisal, S.; Hussain, R.; Tahseen, M.; Loya, A.; Sutton, Chris W.
Targeting of Hypoxia in AQ4N-treated Tumour Xenografts by MALDI-Ion Mobility Separation-Mass Spectrometry Imaging 2013 Djidja, M-C.; Francese, S.; Claude, E.; Loadman, Paul M.; Sutton, Chris W.; Shnyder, Steven D.; Cooper, Patricia A.; Patterson, Laurence H.; Carolan, V.A.; Clench, M.R.
Stem Cell Organoids in Primary Cultures of Human Non-Malignant and Malignant Colon 2017 Tariq, S.; Tahseen, M.; Hassan, M.; Masood, M.A.; Khattak, S.; Syed, A.A.; Ahmad, A.H.; Hussain, M.; Yusuf, M.A.; Sutton, Chris W.
Nipple aspirate fluid - a liquid biopsy for diagnosing breast health 2017 Shaheed, Sadr-ul; Tait, C.; Kyriacou, K.; Mullarkey, J.; Burrill, W.; Patterson, Laurence H.; Linforth, R.; Salhab, M.; Sutton, Chris W.
Evaluation of nipple aspirate fluid as a diagnostic tool for early detection of breast cancer 2018 Shaheed, Sadr-ul; Tait, C.; Kyriacou, K.; Linforth, R.; Salhab, M.; Sutton, Chris W.
Proteomics analysis of colon cancer progression 2019 Clinical Proteomics 16 Saira Saleem, Sahrish Tariq, Iffat Aleem, Sadr-ul Shaheed, Muhammad Tahseen, Aribah Atiq, Sadia Hassan, Muhammad Abu Bakar, Shahid Khattak, Aamir Ali Syed, Asad Hayat Ahmad, Mudassar Hussain, Muhammed Aasim Yusuf and Chris Sutton https://doi.org/10.1186/s12014-019-9264-y